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Predator: Killer of Killers is a 2025 American adult animated science fiction action anthological film directed by Dan Trachtenberg and written by Micho Robert Rutare. Produced by 20th Century Studios and Davis Entertainment, it is the sixth film and eighth installment overall in the Predator franchise.

By October 2024, Trachtenberg, who previously directed Prey (2022), had made a secret film in the franchise, set to be released prior to Predator: Badlands (2025). In April 2025, the film's title and release date were revealed. Animation was provided by The Third Floor.

Predator: Killer of Killers is scheduled to be released on June 6, 2025, in the United States on Hulu and internationally on Disney+.